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46. Prions are infectious proteins that convert normal functional proteins to form misfolded proteins rsulting in fatal disease called Bovine spongiform Encephalopathy or mad cow disease. In this disease a prion protein afects proteins with primary, secondary, tertiary and quartenary structures. Option 5 is correct.
47. Proteins (enzymes) are activated and deactivated according to the requirement of cell metabolic activities. The proteeins undergo various types of regulation like allosteric regulation, phosphorylation and dephoisphorylation. Addition of phosphate group provides charge on protein and makes it polar and removal phosphate group retains the protein to normal nonpolar state. Option 4 is correct.
41. Lipids are macromolecules and are mostly nonpolar. They float in water. They are either saturated or unsaturated. The saturated lipids contain single bonds while unsaturated lipids have C = C (double bonds). These double bonds contribute to high energy of lipids than energy of carbohydrates. Option 5 is correct.
45. A scientific theory is an experimentally proved statement. The experimental data is the evidence to establish the scientific theory. The data support how the things are working and is established as the scientific theory. Option 2 is correct.
44. The synthesis of messenger RNA (mRNA) from DNA is called transcription. The mRNA contains bases and each three bases form a triplet codon that encode for specific amino acid. There are 64 codons encoding for 20 amino acids. The DNA sequence directly not encode for amino acids but the mRNA synthesized from DNA determines the sequence of amino acids. Therefore, option 2 is correct.
The aminoacid sequence or primary structure is produced from mRNA synthesized by DNA. Protein folding is a multistep process. Improper folding in proteins may lead to loss of function of the protein and loss of function of protein may be due to mutation in the DNA.
