Two individuals are each affected by a different single gene

Two individuals are each affected by a different single gene disorder.

       One individual A shows an autosomal dominant disease with

       complete penetrance whereas another individual B shows an

       autosomal recessive disorder. Individual A is not a carrier of the

       mutation for the recessive disorder that affects B. The chance that

       their progeny inherits both the disorders is:

100%

25%

50%

0%

Solution

0%.

If individual A carries autosomal dominant disease for allele A (Aa) and is normal for other allele B (BB). Its genotype will be;

AaBB.

Individual B carries recessive disorder for allele B (bb), but is normal for allele A(AA). Its genotype will be;

AAbb.

Individual A × Individual B

AaBB AAbb.

Gametes: AB, aB Ab.

Offsprings AABb, AaBb.

1. Normal.

1. Autosomal dominant disease and carrier for autosomal recessive disease.