When peptidoglycan is inhibited what processes kill the bact

When peptidoglycan is inhibited, what processes kill the bacteria? List the precursors that would build up within the bacteria if recycling of bactoprenol were inhibited by penicillin, vancomycin, or bacitracin.

Solution

Answer:

The synthesis of the cell wall in bacteria is stoped.Due to inhibition of the peptidoglycon synthesis, autolysis of the cell takes place due to enzymes present in the cell. Inhibition of cell wall synthesis will lead to cell burst due to high osmotic pressure.finally the lysis of the cell takes place.

Penicillin, vancomycin, and bacitracin are the antibiotics which inhibit the bacterial cell. Peptidoglycan is made of the UDP-NAM-NAG linked by pentapeptide. If recycling is inhibited, UDP-NAM-NAG linked by pentapeptide growth takes place in the cytoplasm.

NAM: N-acetyl muramic acid

NAG: N- acetyl glucose amine