Question 1 Why are marker alleles useful to study even thoug

Question 1: Why are marker alleles useful to study even though they do not actually affect the traits being studied? Explain in your own words the logic underlying QTL mapping.

Multiplie choice: The genetic signature of recent positive selection on a locus is ...

Solution

A. A genetic markers is a DNA sequence with a known location on chromosome used to identify individuals are species markets can exhibit two modes of inheritance are there dominant or recessive generally the codominant markers are more informative then dominant market

This genetic marker are used to study the relationship between inherited disease and because of the mutation this enables to determine the correct inheritance pattern of the gene.

A quantitative trait locus qtl is a part of DNA that is related with variation in the phenotype it contains the gene which control the phenotype usually qtl for map by identifying the molecular markers of the particular trait the principles of qtl mapping

1. the likelihood can be calculated by observing phenotype and genotype

2. the estimates of the parameters where the likelihood is highest

3 significance threshold can be obtained by permutation testing.

B. The answer is high frequency and high linkage disequilibrium.

An allele that is in linkage is equilibrium with nearby a marker if young allele. If it is at high frequency must have been driven rapidly to high frequency which means it is under positive selection the higher the frequency the father that is equilibrium extends away from the locusband the stronger is the selection.