QUESTIONS TO ANSWER 1Looking at Janes lab profile it is indi

QUESTIONS TO ANSWER:
1.Looking at Jane’s lab profile, it is indicative of what condition?
2.What are the two most common causes of this condition?
3.Which lab result is critical in the diagnosis of this disease?
4.Discuss the significance of the Hematology results?

Jane L) a 30-year-old woman, was seen in the ER with severe epigastric pain radiating to the back that woke her from sleep. She also complained of nausea and vomiting. The chemistry and hematology tests shown in Tables 2—8 and 2—9 were ordered.

                                                                                                             Jane L.                       Reference Range

Sodi um

140

135-145 mEq/L

Potassium

3.6

3.6—5.0 mEq/L

Chloride

106

98-107 mEq/L

C02

29.0

24.0-34.0 mEq/L

Glucose

116

80-120 mg/dl,

Bilirubin, total

0.2

0.2—1.9 mg/dL

AST

ALP

Protein

26

53

6.8

5-40 IU/L

30-157 IU/L

6.0-8.4 gidL

2120

2121

Reference Range

BUN

13

7—24 mg/dL

Creatinine

1.2

1.2

0.5—1.2 mg/dL

Calcium

9.0

8.8

8.5—10.5 mg/dL

Albumin

4.2

3.5-5.0 g/dL

ALT

23

NT

5—40 IU/L

Amylase

738

265

10-110 IU/L

Lipase

3970*

320

31-186 IU/L

335

NT

13-86 IU/L

Cholesterol

NT

165

Recommended (desirable): < 200 mg/dL

Triglyceride

NT

155

Recommended (desirable): < 250 mg/dL

2120

2121

Reference Range

WBC

RBC

ESR

12.1

4.93

40

10.8

4.76

5-10 x 10⁹/1.

4.0-5.0 x

0—20 mm/h

HDL       35           Recommended (desirable): 60 mg/dL LDL    NT          99           Recommended (desirable): 130 mg/dL *Lipemic sample, results rechecked.

Abbreviations: ALT, alanine aminotransferase; ]GT, gamma glutamyltransferase; HDL, high-density lipoprotein; LDL, low-density lipoprotein; NT, not tested.

Table 2-9 \" HEMATOLOGY

Abbreviations.\' ESR, erythrocyte sedimentation rate; NT, not tested.

	Sodi um	140	135-145 mEq/L
	Potassium	3.6	3.6—5.0 mEq/L
	Chloride	106	98-107 mEq/L
	C02	29.0	24.0-34.0 mEq/L
	Glucose	116	80-120 mg/dl,
	Bilirubin, total	0.2	0.2—1.9 mg/dL
	AST ALP Protein	26 53 6.8	5-40 IU/L 30-157 IU/L 6.0-8.4 gidL
	2120	2121	Reference Range
BUN	13		7—24 mg/dL
Creatinine	1.2	1.2	0.5—1.2 mg/dL
Calcium	9.0	8.8	8.5—10.5 mg/dL
Albumin	4.2		3.5-5.0 g/dL
ALT	23	NT	5—40 IU/L
Amylase	738	265	10-110 IU/L
Lipase	3970*	320	31-186 IU/L
	335	NT	13-86 IU/L
Cholesterol	NT	165	Recommended (desirable): < 200 mg/dL
Triglyceride	NT	155	Recommended (desirable): < 250 mg/dL

Solution

1. elevated levels of amylase and lipase enzymes indiacate that Jane is suffering from acute pancreatitis.

2. Two most important causes of acute pancreatitis are gallstones ad heavy alcohol use.

3. increase in the level of serum amylase and lipase are indicators of acute pancreatitis Amylase helps in the digestion of starch and lipase causes the brak down of lipids.Pancreas produces both these enzymes ,which are then transported to the small intestine.

4. The hematology tests conducted here include RBC and WBC count .Both the RBC and WBC count lie in the normal range . The RBC count is usually done to determine the presence od diseases like anaemia.Rbc count also provides an estimate of the hemoglobin levels in the blood. WBC levels are indicators of infection in the body. Their levels rise in case of bacterial or viral infections.The erythrocyte sedimentation rate(ESR) determines the rate at which the RBS\'s settle down to the bottom in a tube.This test has not been conducted over here.