Adenomatous polyposis coli APC is a protein that is encoded

Adenomatous polyposis coli (APC) is a protein that is encoded by the APC gene. APC acts as a negative regulator of cell growth and homozygosity for APC loss of function alleles is associated with colorectal cancer. A cancer geneticist would describe APC as a [FILL IN THE BLANK] gene. Albinism, the lack of skin pigment, is an autosomal recessive trait controlled by a single gene. What is the probability that two heterozygous parents would produce an albino child? Unless your answer is 0 or 1, please express your answer as a decimal with two significant digits (e.g. 0.67). Based on the preceding question, if these two parents have three children, what is the probability that exactly two of them will be albino? Unless your answer is 0 or 1, please express your answer as a decimal with two significant digits (e.g. 0.67). An individual with a karyotype of 4n-1 can be described as (you may select more than one answer): polyploid euploid diploid aneuploid

Solution

In QUESTION 3:

the ans will be APC as s Tumor Suppresor gene.

Because normally tumor suppresor gene are helpful for the cell. As they perform lots of work cell division, repair DNA mistakes, apoptosis ( normal cell\'s death). If this gene will mutate then its function will loss and the cell progress into cancer. APC also does the same work, so it is atumor suppresor gene.

QUESTION: 4

Two parents are heterozygous and produces a albino child.

Aa                                    X                                        Aa........................................P

AA                       Aa                            Aa                    aa ....................................progeny

AA = normal child, Aa = normal child having a recessive allele, aa = albino child

So, the probability of producing an albino child:     1/4 = 0.25

QUESTION: 5

Two heterozygous parent have three children. So, the probability of having two albino child is : 2/3 = 0.67

QUESTION : 6

An indivisual with karyotype is 4n-1. It is described as Aneuploid. Aneuploidy is one type of chromosomal mutation where chromosomal number either greater or lesser than wild type.

For example: Aneuploid condition 2n-1 is called monosomic where one chromosome out of 2 is absent in its diploid progenitor. Using this logic it is an aneuploid, where 4n means tetraploid.