Propose a pathways to explain how the ectoderm and the notoc

Propose a pathway(s) to explain how the ectoderm and the notochord block the ability of the endoderm to express liver-specific genes during liver formation.

Solution

Some endodermal cells lie in the yolk sac of the cell, a subset of which move forward for the formation of the liver. Fox-A proteins are responsible for the expression of liver-specific genes It is the thickening of the intestinal rod tissues that is formed from the ectoderm that blocks the formation of inner organ tissue at the initial stage. Morphogenesis takes place to facilitate gene expression in the liver. The amniotes hhex and prox1 are responsible for liver gene expression. The loss of hhex can retard the formation of liver reduce its size.

The mutants from the notochord block the endoderm to express liver-specific at the early stage liver formation.