Below is a chart detailing the various checkpoints during th
Below is a chart detailing the various checkpoints during the cell cycle. Complete the chat by filling in the missing parts. (One label will be used more than once)
Solution
In a cell cycle, there are many checkpoints to control the proceedings of the cell into various stages.This helps in preventing the damaged cells from dividing and further produce mutated cells. There are mainly three checkpoints G1, G2 & M checkpoints. G1 checkpoint- It is a cell cycle checkpoint where a cell is commited to enter the diving phase and thus is being checked for any errors at this point.If the DNA is proper it proceeds into S Phase where the DNA replication occurs.But the cell is stopped from proceeding into G2 stage if there is any DNA damage and it is unrepairable. G2 Checkpointr the DNA replication in S phase once again the DNA is checked for errors i.e, if the replication occurred properly to enter the mitotic phase where the actual division of the cell occurs. Thus one can say this is a mitotic checkpoint and would arrest the cell in this phase if the DNA is damaged and not replicated. M check point- This is a metaphase checkpoint or spindle assembly checkpoint.As the name indicates at this point the cell is mainly checked for the alignment of the chromosomes at the centre of the cell.The celll proceeds further if all the duplicated chromosomes are ready with sisters chromatids to seperate and would stop if the alignmenet of the chromosomes is improper.