Describe all four level of insulin structure including the s

Describe all four level of insulin structure, including the stabilizing forces and how they are formed in each level.

Solution

The hormone insulin is a protein consisting of 2 polypeptide chains.

Primary structure: A chain is a linear sequence of 21 amino acid residues and B chain has 30 amino acid residues bonded together by peptide bonds.

Secondary structure: A chain, contains 2 sections of alpha helix and the B chain also consists of a larger section of alpha-helix. A and B joined by disulfide bonds.

Tertiary structure: is stabilised by disulphide bridges between thiol groups of cysteine amino acids And by salt bridges as well as Van der Waal\'s forces. There are 3 disulphide bridges formed between the A and B chains and one within the A chain.