Three genes in the lab bug an insect specially bred for gene
Three genes in the lab bug, an insect specially bred for genetics problems, are linked as indicated in the following gene map:
-----------------A/a------10 cM-----B/b------------------25 cM-------------------C/c------
Parental AAbbCC and aaBBcc lab bugs are mated to yield an AaBbCc F1 generation. The F1 individuals are then test-crossed with aabbcc lab bugs. Assuming that 1,000 test-cross offspring (the lab bug is very prolific) hatch, predict the number of test-cross offspring exhibiting non-recombinant and recombinant phenotypes. (For simplicity, ignore the possibility of double crossover offspring.)
Type of
Genotype Crossover # Offspring
AabbCc Non-recombinant
aaBbcc Non-recombinant
Aabbcc Recombinant
aaBbCc Recombinant
AaBbcc Recombinant
aabbCc Recombinant
(HINT: Look at the parental generation to see which alleles are linked together.)
**Please write in detail so I can learn from it! Thank you!!
Solution
Answer:
Genotype Crossover # Offspring
AabbCc Non-recombinant 325
aaBbcc Non-recombinant 325
Aabbcc Recombinant 125
aaBbCc Recombinant 125
AaBbcc Recombinant 50
aabbCc Recombinant 50
Explanation:
Linked gene configuration= AbC/aBc
Map distance = recombination frequency
Single cross over b/w a & b produces the following progeny in 10/100 * 1000 = 100
ABc/abc = 50
abC/abc=50
Single cross over b/w b & c produces the following progeny in 25/100 * 1000 = 250
Abc/abc= 125
aBC/abc=125
Total recombinants = 100 + 250 = 350
Non-recombinants = 1000-350 = 650
AabbCc=325
aaBbcc=325

