The following schematic drawing shows two integrin molecules

The following schematic drawing shows two integrin molecules. Which molecule (a or b) is depicted in its active configuration? Which side of the plasma membrane (1 or 2) represents the cytosol?

a; 1

a; 2

b; 1

b; 2

Solution

B; 2.

Side 1 represents extracellular surface of the cell and side 2 represents cytosol.