Now imagine a region of DNA the ratio of histone H2A to H2B

Now imagine a region of DNA, the ratio of histone H2A to H2B is the same, but the histone H1 to H2B can change. If the amount of H1 increased relative to the amount of what would the effect be on transcription of that region? Why? List and describe three levels of chromatin structure in order from least compact to compact.

Solution

5). a). Chromosomes contain DNA (deoxyribonucleic acid) bound proteins called “histones,” which serve to “package” the DNA and thereby controls its functions. Histone H1 is an essential component of chromatin. The nucleosomes are linked to higher order structures by the HI histones, the histone H5 serve the similar function as that of H1. H1 acts as a repressor of replication, thus, the region with high H1 amount have decreased rate of transcription.

b). The three levels of chromatin structure in order from least compact to more compact are, euchromatin, heterochromatin and metaphase chromosome.