Homework SourseWould the lagging or leading strand be more affected by a mu
Would the lagging or leading strand be more affected by a mutation that prevents ligase from working?
Would the lagging or leading strand be more affected by a mutation that prevents ligase from working?
Solution
DNA ligase is essential for joining okazaki fragments during replication and for completing short patch DNA synthesis occurring in DNA repair process. Any mutation in DNA ligase can affect leading strand first and thus DNA replication.
