What are the three classes of drugs that doctors tend to pre
What are the three classes of drugs that doctors tend to prescribe for GERD patients and how does each one work? Try to make an educated guess with respect to pH as to how they work.
What are the three classes of drugs that doctors tend to prescribe for GERD patients and how does each one work? Try to make an educated guess with respect to pH as to how they work.
Solution
Answer-
1class-H (Histamine)2 blocker-Histamin stimulates acid production and down the PH of stomach so H2 blockers are used to suppress acid production.eg.-Nizatidine,Famotidine,Ranitidine
2class-Proton pump inhibitors(PPI)-It is most significataly more effective in GERD.DUE to proton pump Hydrogen ions from cells pumped into the stomach and increase acidic level so proton pump inhibitors are used to inhibite these proton pumps.eg-PANTOPRAZOLE(protonix),Esomeprazole(Nexium)
3class-Promotility agents-Pramotiliting agents work by stimulating the muscles of gastrointestinal tract which may help prevent acids from stying in the stomach too long .eg-Metoclopramide(Reglan)
