In Graves disease the immune system makes antibodies that st

In Grave\'s disease, the immune system makes antibodies that stimulate TSH receptors on the thyroid gland. What effect does this have on Krista\'s thyroid? Why is Krista\'s TSH level low instead of high?

Solution

5. The antibodies produced in graves disease stimulate TSH receptors on thyroid gland to secrete thyroxine. There occurs a mis-interpretation that TSH levels are too high because antibodies mimic TSH even in its absence. hence results in a goitre.

6. Antibodies from Graves disease stimulate her TSH receptors of Thyroid gland, creating illusion that her body has lot of TSH. As a result, the brain signals to stop the secretion of more TSH hence causing low levels of TSH.