The nephron loop is responsible for approximately 25 of the

The nephron loop is responsible for approximately 25% of the reabsorption of sodium. Loop diuretics cause an overall __________________ in the reabsorption of sodium in this region resulting in a(n) ________________________ in the osmolarity of the tubular filtrate.

Solution

1. Overall DECREASE in the reabsorption of sodium resulting in a DECREASE in the osmolarity.

When sidium reabsorption is less the medulla becomes concentrated be vause water molevules move to combat the reducedvsodium ckncentration.

So osmolarity decreases.