role alternative splicing and rna editing in the role of str
role alternative splicing and rna editing in the role of structural and functional diversity in gene products
Solution
Answer:
Alternative splicing and rna editing are important mechanisms to generate a large number of mRNA and protein isoforms from the surprisingly low number of genes.
Alternative splicing provides evolutionary flexibility. A single point mutation may cause a given exon to be occasionally excluded or included from a transcript during splicing, allowing production of a new protein isoform without loss of the original protein.
RNA editing generates RNA and protein diversity in eukaryotes and results in specific amino acid substitutions, deletions, and changes in gene expression levels.
RNA editing can create proteins with slightly different functions to use in specialized circumstances. An example is synthesis of two versions of apolipoprotein B from a single gene each having different functions. RNA editing helps in generation of Antibody Diversity
RNA editing is also shown as a Regulator of Gene Expression, it could also bring about gene silencing
