f a new spontaneous mutation happens that confers antibiotic
f a new spontaneous mutation happens that confers antibiotic resistance, what is its most likely effect on fitness relative to the un-mutated (wild-type) strain, if they are compared when growing in the absence of antibiotics?
Deleterious relative to unmutated wild type
Advantageous relative to unmutated wild type because it confers resistance
The same relative to unmutated wild type
Insufficient information to choose the best answer
| A. | Deleterious relative to unmutated wild type |
| B. | Advantageous relative to unmutated wild type because it confers resistance |
| C. | The same relative to unmutated wild type |
| D. | Insufficient information to choose the best answer |
Solution
Answer: b. Advantageous relative to unmutated wild type because it confers resistance
Reason:
In the above case, it has clearly illustrated that new spontaneous mutation happens that confers antibiotic resistance, what is its most likely effect on fitness relative to the un-mutated (wild-type) strain, so that a few bacterial cells that are having antibiotic resistant genes can generate a fluid environment that can neutralize any antibiotic. Therefore, it can depicted that these mutations are advantageous relative to unmutated wild type because it confers resistance. AmpR gene expression: transformation of the HB 101 cells with plasmids result in the production of beta-lactamase that resists the ampicillin antibiotic and makes it useless. Plasmids are small circular DNA molecules present in the chromosomal regions and they possess the property of self- replication in order to produce the products against the antibiotics by huge multiplication or reproduction.
