HO HO H2C NADHH H2C OH NAD CH CH2 CHOH O OH OH oketoglutaric

HO HO H2C NADH+H H2C OH NAD CH CH2 CHOH O OH OH o-ketoglutaric acid lsocitric acid 15) Which compound is oxidized in the reaction above shown Figure? A) Isocitric acid and o-ketoglutaric acid B) a-ketoglutaric acid C) NAD+ D) NADH

Solution

Answer is Isocitric acid

Isocitric acid is oxidized and loses a molecule of CO2, forming alpha-ketoglutaric acid. The H+ is passed on to the NAD+, which is reduced to NADH + H⁺.