8 A human T lymphocyte is infected by a HIV The viral genome

8. A human T lymphocyte is infected by a HIV. The viral genome present inside the cell can be any of the following molecules except _________.

A. ssDNA

B. dsDNA

C. ssRNA

D. dsRNA

Solution

dsRNA

Retroviruses have a single stranded RNA genome. Two copies of the sense strand of the genome are present with the viral particle. When they infect a T cell, the single stranded RNA is converted into dsDNA copy by the reverse transcriptase. Replication and transcription occur from this dsDNA intermediate, the provirus, whihc is integrated into the host cell genome by a viral integrase enzye,.