Which is better a loss of genetic material or a duplication

Which is better, a loss of genetic material or a duplication?  

Solution

The loss of genetic material or duplication has both not much detrimental or beneficial to the species survival. The loss of genetic material or gene duplication may induce cancer if the genetic material undergoes mutation followed by indels (insertions or duplication & deletions). For example, duplication of oncogenenes may result in cancer and loss of genetic material to code for tumor suppressor protein (P53) may cause inability of a cell to suppress \"tumor cell proteins\". Therefore, both are not better

For example, a loss of genetic material or duplication in embryonic Homeobox-containing genes forms homeodomain protein motif result in \"disability in the phenotype\" becuase these genes are highly conserved in different species during evolution and produces adaptive structural modifications within the species. Hox genes have evolved through “tandem duplication” as synthesized Hox proteins are exhibiting greater similarity to homeodomains formed in other species when compared to the proteins that are produced by adjacent genes within their own Hox genes cluster.