List 3 key differences between a benign and malignant infect

List 3 key differences between a benign and malignant infection with a high-risk HPV with respect to the cells involved, the state of the viral genome and the viral gene products.

Solution

Benign infection of HPV Malignant infection of HPV Divergent differentiation of a single line of parenchymal cells. Mesenchymal origin,fleshy, fibrosarcoma, synovial sarcoma. Cystic adenoma containing papillary epithelial growth. Epithelial origin (from any of three germ cells layers), carcinoma, adenocarcinoma, squamous cell carcinoma Tumours of mesenchymal tissue follow this rule – fibroma, chondroma, osteoma, lipoma. Divergent differentiation of single line of parenchymal cells. E.g. Cystadenoma E. g. Adenocarcinoma,