Describe the process of events involved in ligand production

Describe the process of events involved in ligand production to exocytosis..

I need help answering question #2 of my study guide

sample Essay Questions: Include diagrams/flow charts and provide detail. Approx. 1 page. Midterms are 50 minutes in duration and 190points, you will be given up to 5-6 essay questions you must answer 2-3 in detail. Some short answer questions will also be given What am I looking for in an essay question? Diagrams must be clearly labeled and self-explanatory Textual explanations must be logical and in the correct order Details matter, write as much about a process as you know PowerPoint slides have details but may not be complete, you should be taking extra notes in cla Sample Questions from the first set of PowerPoint slides 1. Describe the role signal sequences play in protein localization. a. NES, NLS, Stop start, ER signal sequences 2. Describe the process of events involved in ligand production to exocytosis.tt a. PowerPoint Slide 6 plus written details 3. Post transcriptional modifications. Discuss a. 5\' capping, splicing, poly A tail 4. Describe three different mechanisms of signal termination a. Inhibitors extracellular, receptor inhibitors, internalization, phosphorylation/dephosphorylation 5. Give an account of the role vesicle tethering plays in endocytosis. a. SNARES V and T, Rab effectors, tethering docking fusion 6. Protein glycosylation, discuss, its importance and the process of glycosylation a. Occurs in ER, modified in Golgi, etc..... 7. Autocrine, paracrine and endocrine. Discuss the differences between these signaling mechanisms. 8. Write an account how signaling can be terminated at the level of receptors 9. Different cells can react differently to the same signal. Discuss a. Example acetylcholine 10. outline the process of plasma membrane receptor production to its final destination 11. Two major populations of ribosome exist in our cells. Discuss In one or two sentences explain the function or role of each Dynamin, FG repeats, Clathrin, Nuclear localization/export signals, signal recognition particles, lysosome, nuclear pore complexes, stop-start sequences, exocytosis, endocytosis, Rab5, importins, exportins, Rab11, Rab7, cargo, v SNARES, t SNARES Rab effectors Sec61 complexes

Solution

Exocytosis is active transport mechanism in which a cell transports molecules out of the cell by expelling them in an energy dependant process.

Specific ligands release histamine by the regulated pathway to bind receptors on the mast cell surface. Histamine is responsible for many unpleasant symptoms like allergic reactions. massive exocytosis occurs all over the cell surface.

Exocytosis is restricted to the region if the ligand is artificially attached to a solid bead to interact only with a localized region of the mast cell surface.