Why is it beneficial that so many enzymes have a binding sit

Why is it beneficial that so many enzymes have a binding site for ATP?

Solution

Within the cells, the free energy change liberated by ATP hydrolysis is = 12 kJ/mol. (More than that is liberated during the standard conditions; this is due to high ATP to ADP ratio within the cell). One important factor that results in the release of highly exergonic free energies of phosphoric acid and anhydrides when they are hydrolysed is, separation of like charges, i.e. the separation of phosphate groups relieves the high electrostatic forces and liberates a high amount of energy. Delta G = -30.5 kJ/mol.

This energy could drive the metabolic reaction forward in almost all the cells, therefore it is important that the cells must possess binding sites for ATP. For example, Na/K pump allows the active transport of ions, which needs energy and this energy is provided by the hydrolysis of ATP, this is mediated by an enzyme known as Na/K-ATPase. It is called a P-type ion pump because the transport protein is phosphorylated by the ATP interactions and brings conformational changes to its structure.