1 A B cell area in a lymph node is analogous to a in the s

1 . A B cell area in a lymph node is analogous to a _______ in the spleen.

2. A helper T cell...

3. A T cell area in a lymph node is analogous to a _______ in the spleen.

4. Consider high endothelial venules. Where are they located?

5. Consider high endothelial venules. What kind of lymphocytes do they interact with?

6. Does passive immunization require the production of memory cells in the person passively
immunized?

7. How can your immune system be trained to protect you against a pathogen that you have
never been infected with?

8. Which of the following is not one of the functions of secondary lymphoid tissues?

9. What is the source of lymph fluid?

10 .Recognition of antigen is required for...

Solution

1.D (Follicles,rich in B-lymphocytes, Active immune response through humoral and cell-mediated pathways.B cells in lymph nodes produce antibodies. Each antibody has a single predetermined target, an antigen, that it can bind to. These circulate throughout the bloodstream and if they find this target, bind to it and stimulate an immune response.)

2.B(Mature T_h cells express the surface protein CD4 and are referred to as CD4⁺ T cells. Such CD4⁺ T cells are generally treated as having a pre-defined role as helper T cells within the immune system.)

3.B(\"periarteriolar lymphoid sheaths\" (PALS), rich in T-lymphocytes are similar to T cells in lymph node and produce active immune response through humoral and cell-mediated pathways.)

4.C(HEVs enable lymphocytes circulating in the blood to directly enter a lymph node (by crossing through the HEV).

5.A(Naïve T cells in the circulation regularly move through the lymph nodes via HEV in order to scan the APC for foreign antigens. When they encounter such an antigen, the cell becomes activated, resulting in the immune system mounting a response against the causative agent of the infection.

6.NO.(Passive immunity is the transfer of active humoral immunity in the form of ready-made antibodies.)

7.D(Vaccination is the administration of antigenic material (a vaccine) to stimulate an individual\'s immune system to develop adaptive immunity to a pathogen. )

8.C(maintain mature naive lymphocytes and initiate an adaptive immune responsE,sites of lymphocyte activation by antigens which leads to clonal expansion and affinity maturation. Mature lymphocytes recirculate between the blood and the peripheral lymphoid organs until they encounter their specific antigen.Also provides the environment for the foreign or altered native molecules (antigens) to interact with the lymphocytes.)

9.A(As the blood and the surrounding cells continually add and remove substances from the interstitial fluid)

10.