It is possible to have a nonsense mutation occur in the star

It is possible to have a nonsense mutation occur in the start codon. True or False?

Solution

Its true. mutation can occur anywhere in the DNA. A nonsense mutation can occur in start codon if a frame shift mutation is occurred in DNA. Suppose AUG ( start codon) follows by a AAA ( lysine ) sequence and a frame shift mutation is occurred then it can merged like this A UGA AA .( UGA is a stop codon).