Which of the following is NOT a difference between the smoot

Which of the following is NOT a difference between the smooth ER and the rough ER? The rough ER has ribosomes; the smooth ER does not. The smooth ER works to detoxify poisons; the rough ER aren\'t got time for that. The smooth ER creates lipids while the rough ER makes a lot of membrane proteins. The smooth ER makes phospholipids, but the rough ER does not. The rough ER makes secretory proteins; the smooth ER does not.

Solution

The smooth ER are engaged in generation of lipids and phospholipids along with detoxification of poisons from the cells. On the other hand, rough ER are engaged in genertion of proteins since they carry ribosomes on their surface where translation takes place. Importantly, the rough ER are involved only in generation of primary sequence of proteins i.e. a polypeptide sequence. They do not help in folding or generation of secondary structure of proteins. Moreover, the polypeptide synthesized on rough ER contains a leader seqeunce which helps the nascent polypeptide to golgi apparatus for transport. This suggests that the rough ER are not involved in generationof secretory protein.

Thus, this information suggests that choice E is correct.