If mutation occurs causing transcription of a gene to occur

If mutation occurs causing transcription of a gene to occur on both strands of the DNA in the same cell, what affect would you expect that to have on the production of protein for the gene?

Solution

In normal case only one strand of DNA code in transcription. Now suppose both strands of DNA causing transcription of genes by any means though the coding sequence of one gene will always be on one strand. other side transcription will often give an anti-sense transcript. Antisense transcription may be an unwanted byproduct of gene regulation. However there are also examples where the antisense transcripts have shown with functions as long non-coding RNAs

Example, the Xist and Tsix transcripts involved in X-chromosome inactivation.

Also certain genes encode multiple genes on the same strand of DNA in different reading frames for example the programmed frameshifting that occurs in the gag-pol gene of HIV).