In a given population of 610 individuals the gene frequency

In a given population of 610 individuals, the gene frequency of the L^m and L^n alleles were found to be 0.62 and 0.38 receptively. Calculate the number of individuals with M, MN, and N blood types.

Solution

Answer :

Lm=0.62

Ln=0.38

Total individuals = 610

p=Lm=0.62

q=Ln=0.38

Hardy weinberg equation

p^2 +2pq+q^2=1

p^2 = number of M individuals

q^2=number of N individuals

2pq=number of MN individuals

p^2=0.62 x 0.62 = 0.384

q^2 = 0.38 x 0.38 =0.144

2pq= 2 x 0.62 x 0.38 = 0.47

Among 200 individuals

(1) 38% are p^2, that means 610 x 0.384 =234 are M blood type individuals

(2) 610 x 0.144 =88 are N blood type individuals

(3) 610 x 0.47 =287 are MN blood type individuals