Calculate VK at room temperature for an intracellular concen

Calculate V_K at room temperature for an intracellular concentration of 10 and an outward concentration of 190.

Put V for units even though the answer is calculated in mV. You dont have to do any other conversion for this. Put a space between the number and the unit.

Solution

V_k = (RT/zF) ln(outer/inner)

R is the gas constant, F is Faraday\'s constant. Thus, calculation of V_k requires temperature (T in Kelvin), ionic concentration (outer and inner) and valence (z). Valence is not provided in the question. Assuming that all ions are monovalent (i.e. z = 1), we calculate V_k:

R = 8.314 J.K¹.mol¹, F = 96485 C.mol¹, T = 25°C 298 K, outer = 190, and inner = 10

V_k = (8.314×298/96485) ln(190/10) = 0.026×2.944 = 0.075 Volts*

(*I am not sure by what you mean by \"Put V for units even though the answer is calculated in mV\". The answer is 0.075 V = 75 mV; if you wanted your answer in volts, it is 0.075 V. If you wanted the answer to state mV as volts, the answer is 75 V)