94 Wed 102 PM session masteringaandpcommycttemviewoffsetm ne
Solution
4. Energized cocked myosin head
3.ATP
This is because at rest, the myosin head is bound to an ATP molecule in a low-energy configuration . At this time it is unable to access the cross-bridge binding sites on the actin.The myosin head can hydrolyze ATP into ADP and an inorganic phosphate ion. A portion of the energy released in this reaction changes the shape of the myosin head and promotes it to a high-energy configuration.
1.
2.Actin binding sites exposed
When intracellular calcium levels are low, the muscle cell is relaxed, and tropomyosin molecules block the active binding sites on actin.Ca2+ levels are taken from cytosol and once a sufficient level of calcium is reached, binding sites of actin are exposed for cross bridge Once binding sites on actin are exposed, the events of the cross bridge cycle occur in rapid succession. The tropomyosin is removed when sufficient calcium is present.
