Following uptake of glucose by GLUT1 in the islets of Langer

Following uptake of glucose by GLUT_1 in the islets of Langerhans, put the correct events in the first to last, using the items numbered below. ATP mediated phosphorylation of the potassium channel Cell depolarizes Cell hyperpolarizes Glycolysis and citric acid cycle Insulin is synthesized in the nucleus Pre-made vesicles containing insulin fuse with the cell membrane Voltage gated Ca++ channels open Voltage gated Na+ channels open 1, 3, 7, 8 3, 4, 5, 6 4, 1, 2, 7, 6 7, 1, 6, 2, 4 3, 2, 1, 5, 6 A 45 year old patient comes to the ER complaining of pain in the center of her body. She continues to moan, loudly, is pale and insists that she needs surgery. You are uncertain of what may be wrong so you as the lab to check her blood levels of which of the following enzymes to determine if she is suffering from a heart attack? Acid Phosphatase Alkaline Phosphatase Amylase Creatine Kinase Glyceraidehyde 3-phosphate Dehydrogenase Congenital disorders of glycosylation (CDG) is an umbrella term for a rapidly expanding group of rare genetic, metabolism disorders due to defects in complex chemical process known as glycosylation. During your first year as an internal medicine resident in the neonatal intensive care unit, you are asked to interpret the results for testing for this disorder using a microscope and a slide that has been stained for glycosylation. Which cellular structure would be the MOST LIKELY site where you would see a noticeable difference from normal? Cell membrane Mitochondria Smooth endoplasmic reticulum Peroxisomes Lysosomes Following a visit to his physician, George, a 73 year old man receives a phone call informing him that his PSA is elevated. He calls you, since he knows that you did well on your 4388 Mammalian Physiology class and asks what the elevation in his PSA levels indicates. You explain that PSA stands for: Pancreas selectee antigen- he needs to be seen for pancreatic disease. Pulmonary striatus aldehyde- he probably has lung cancer. Prostate specific antigen- he needs to be checked for prostate cancer. Pyruvate synthase amylase - he needs to be screened for diabetes. You are not sure- you never even discussed that in class.

Solution

29. C

30. D.
If heart muscles are started to dying it secret creatine kinase.
Alkaline phosphatase - Removal of phosphate group
Acid phosphatase - Hydrolysis organic phosphate
Glyceraldehyde 3-phosphate dehydrogenase - Glycolysis
Amylase - Conversion of starch to sugar.

31.C Smooth Endoplasmic reticulum
CDG is due to alternation of dolichol biosynthesis severly affect the N-glycosylation process. Dolichol is the by product of Cholestrol synthesis occurs in SER.

32. C. Prostate specific antigen -need to check for prostate cancer.