10 What are 3 reasons that the generation of antibodies is u

10. What are 3 reasons that the generation of antibodies is useful for the immune response?

Solution

What are 3 reasons that the generation of antibodies is useful for the immune response?

Generation of antibodies forms the humoral immune response. These antibodies are produced from B cells upon antigenic stimulus.

Functions of antibodies are diverse,

1. Neutralization of pathogens-

Once the antibodies recognize the antigens, the binding occurs outside the cell. The binding of antibody prevents the entry of pathogen into the cells and protects the cells from infection or destruction of host cells.

2. Activation of effector cells-

Antibodies through their Fc fragments activate other immune cells (effector cells- macrophages, T cells mast cells etc) and eliminate the pathogens.

3. Activation of complement system-

Once antibodies bound to the antigens, antigens-antibody complexes are formed. These complexes in turn activate a complex set of reactions known as complement cascade. These complements which serve as chemotactic factors, which enables phagocytes to destroy pathogens (Bacteria).