1Due to redundancy in the genetic code a sequence of amino a

(1)Due to redundancy in the genetic code, a sequence of amino acids could be encoded by several DNA sequences. For a ten amino acid long protein fragment, what is the lower and upper bound for the number of possible DNA sequences that can encode this protein sequence?

(2) Describe a method for finding,within a collection of proteinsequences, the longest English languageword. The English wordmay be a subsequence within any protein sequencein the set. Identify the assumptions of your method.

Solution

Q.No 1

All the N-terminal domain name regarding a protein coding series is without a doubt specialized in many ways. Earliest, the idea constantly has start codon, spread out with a suitable way away with a ribosomal bandaging site. Second, plenty of cryptography regions have particular functions inside the N terminus, many of these as protein export tags and lipoprotein cleavage not to mention bond tags. These transpire with the beginning of some cryptography section, so will be classified Mind domains. A protein domain is a series regarding proteins which in turn flip the fairly self employed not to mention which you\'ll find evolutionarily shuffled as a unit among the different protein coding regions. The DNA sequence regarding such domains must keep up in-frame translation, thus is a various regarding several bases. Protein domains are inside of a protein coding series, these products are called Intrinsic domains. Sure Internal domains have actual capabilities in protein cleavage or even splicing and so are classified Exclusive Intrinsic domains. In the same way, these C-terminal domain name regarding a protein is specialized, made up of at the least a stop codon. Additional specialized functions, similar to degradation tags, are essential to generally be with the non plus ultra C-terminus. Again, these domains cannot element anytime internal to a cryptography section, and so are classified Quarter domains.

Q.No 2

Too many numbers of protein sequencing banks are available for finding the protein sequences. NCBI, EMBL,DDBJ, PDB and PIR are most commonly used protein databases. Using its duration of ~27,000 towards ~33,000 proteins (depending at the splice isoform), titin is without a doubt the largest known protein. Moreover, these cistron intended for titin incorporates the largest quantity of exons (363) discovered in almost any solo cistron, plus the greatest single exon (17,106 bp).

Longest English language word obtained from titin protein sequences GenBank: CAA62188.