Consider the following characteristics of a given pedigree W
Consider the following characteristics of a given pedigree. What mode of inheritance is most likely?
-Males and females are equally affected
-Two unaffected parents can have an affected child
-In families in which the parents are unaffected but the children are affected, 1/4 of the children are affected
A) Y-linked B)Autosomal recessive C) X-linked recessive D) X-linked dominant E)Autosomal dominant
Solution
Answer:
B)Autosomal recessive
A: unaffected (dominant)
a: affected (recessive)
Aa (unaffected) x Aa (unaffected)-------------Parents
| A | a | |
| A | AA (unaffected) | Aa (unaffected) |
| a | Aa (unaffected) | aa (affected) |
