1 a What are two concerns regarding biomedical materials whe

1. (a) What are two concerns regarding biomedical materials when using gas treatment (ozone, H₂O₂, ClO₂, EtO) to sterilize parts?

(b) This would likely be more of a problem which class of material: metal, ceramic or plastic materials, and why?

Solution

(a) What are two concerns regarding biomedical materials when using gas treatment (ozone, H₂O₂, ClO₂, EtO) to sterilize parts?

Answer: Biomedical material are heat sensitive and they possess low thermal stability and may undergo denaturation when exposed to inappropriate concentrations of gaseous sterilizing agents such as ozone, H₂O₂, ClO₂, ethylene oxide finally result in bulk and surface modification of biomedical materials. Therefore, it is essential concern to calculate decimal reduction time for specific sterilization & bio-burden

2. It is essential to know the gas dynamics such as gas penetration, gas sorption before sterilizing biomedical materials. The sterilizing parts of the biomedical material may delicate and sensitive therefore, the concentration of the gaseous sterilizing agent must be calculated before being sterilization process

Part-(b) This would likely be more of a problem which class of material: metal, ceramic or plastic materials, and why?

Answer: Metal based biomedical material are mainly containing metal often undergo oxidation to form epoxies or oxides on their surface due to sterilizing gas penetration, gas sorption finally undergo surface modification & denaturation