onnect MMcGrawHill Shop CHEM 475Spring17ZHANG I Activities a

onnect MMcGraw-Hill Shop CHEM 475-Spring17-ZHANG I Activities and Due Dates I Homework 2 Print Icalculator MPeriodic Table estion 7 of 20 Incorrect Incorrect Sapling Learning The sarcoplasmic reticulum Ca2 ATPase (SERCA) pumps Ca2\" out of the cytoplasm and into the sarcoplasmic reticulum of muscle cells. Muscle contraction occurs in response to the rapid rise of Ca in the ions must removed form the muscle relaxation to occur. SERCA removes the calcium ions, enabling muscle relaxation. SERCA is a protein with a nudeotide-binding domain (N), a domain that accepts a phosphoryl group (P), and an actuator domain (A) A transmembrane domain binds calcium ions. From what you know of the mechanism of Ca2 transport, which of the following binding patterns are observed at any point? Select all that apply. Assume that only the species mentioned are bound. For example, if ADP is not mentioned, it is not bound. M 2 ca bound 2Ca2 ATP bound 2 ca and ADP bound ATP bound 2 Ca2 ADP, and P, bound AMP bound One of your answers is incorrect Reconsider the order of release of Ca ADP, and P Pi bound O Previous 8 Give up & view Soution a Try Again o Next a Exit 0 e

Solution

2Ca²⁺ bound

2Ca²⁺, ATP bound

ATP bound

when Ca²⁺ is taken up by the sarcoplasmic reticulum by the binding of Ca²⁺ with ATP. ATP is then converted to ADP and Pi and energy. This energy is used up for the entry of Ca²⁺ ions into the sarcoplasmic reticulum.