Carolyn a 58yearold female came into your clinic with a chie

Carolyn, a 58-year-old female, came into your clinic with a chief complaint of acute abdominal pain in the upper right quadrant. Murphy’s sign was positive, marked jaundice was observed, and history revealed recent weight loss, fatigue, and increased alcohol consumption due to a recent divorce. Carolyn denies IV drug use. Lab results show increased bilirubin, AST, ALT, and decreased serum albumin. A rapid HIV test was negative. 1. List 3 differential diagnoses and include your reasoning behind each. 2. What is the best diagnosis? Explain how you came to this conclusion. 3. Explain the pathophysiology of the following symptoms: Increased bilirubin: Fatigue: Weight loss:

Solution

Diagnosis for hepatisis , haemolytic anaemia and possible diagnosis for blockade of bile ducts should be recommended as these are the reasons for increased bilirubin . Best diagnosis is test for hepatisis ( as patient mentioned the symptoms of light jaundice, fatigue and increased bilirubin levels) Pathophysiology of increased bilirubin , fatigue and weight loss - hepatitis, liver cirrhosis