Overall is glycolysis an endergonic or exergonic pathway Whi

Overall, is glycolysis an endergonic or exergonic pathway? Which steps of glycolysis use ATP? make ATP or NADH? are catalyzed by kinases? are catalyzed by dehydrogenases? What is the net energy yield (ATP and MADH) for one glucose?

Solution

Answer:

1). Overall, glycolysis is an exergonic reaction as it releases more energy than the energy utilized in the process.

2).

a). ATP used in the first and third steps of glycolysis

Glucose + ATP----Glucose-6-phosphate + ADP + ip

Fructose-6-phosphate + ATP--- Fructose-1, 6-bisphosphate + ADP + ip

b). ATP or NADH are produced in 6th, 7th and 10th step of the glycolysis.

c). First, third, seventh and tenth (step) reactions of glycolysis are catalyzed by kinase enzymes.

d). The sixth step (reaction) of glycolysis is catalyzed by dehydrogenase enzyme.

3).

During glycolysis two ATPs are utilized, 4 ATPs and two NADHs are released. Each NADH produces three ATP. So total net yeild of ATP from glycolysis is 8ATP (10-2=8).