Which of the following statements regarding enzyme inhibitor

Which of the following statements regarding enzyme inhibitors is INCORRECT?

A:Both Vmax and Km change in the presence of a mixed inhibitor.

B:Vmax decreases in the presence of an uncompetitive inhibitor.

C: Comepetitve inhibitors result in formation of an ESI complex.

D:Enzymes can still achieve Vmax in the presence of a competitive inhibitor.

E:Km decreases in the presence of an uncompetitive inhibitor.

-An explanation would be great!

Solution

The false statement is competitive inhibitor form ESI complex

Because in competitive inhibition, inhibitor bind to the enzyme active site that prevent the substrate binding to the active site. Finally, enzyme inhibitor complex is formed not an ESI complex.

Hence, the statement C is false.