Based on this table and the structures of the amino acids Fi

Based on this table and the structures of the amino acids (Figure 5.14 in your textbook), how many negatively charged amino acids are present in this molecule?

Based on this table and the structures of the amino acids, how many positively charged amino acids are present in this molecule?

What is the maximum number disulfide bonds this protein can have?

This protein has 179 amino acids. Based on the amino acid composition, this protein is      

a.negatively charged

b.predominantly neutral

c.positively charged

sin Inhibitor Tr Amino acid Amino acid alanine leucine 14 lysine arginine asparagine methionine aspartic acid 12 phenylalanine proline cysteine glutamic acid Serine glutamine 12 threonine glycine 15 tryptophan 5 tyrosine histidine valine isoleucine 17 11 16 12

Solution

Based on this table and the structures of the amino acids (Figure 5.14 in your textbook), how many negatively charged amino acids are present in this molecule?

Aspartic acid =12

Glutamic acid = 9

Total = 21 negatively charged amino acids

Based on this table and the structures of the amino acids, how many positively charged amino acids are present in this molecule?

Lysine=8

Arginine= 14

Histidine=5

Total = 27 positively charged amino acids

What is the maximum number disulfide bonds this protein can have?

Two cysteine amino acids together make one disulfide bond

So 4 cysteines make total of 2 disulfide bonds

This protein has 179 amino acids. Based on the amino acid composition, this protein is      

Since there are more positively charged amino acids, this protein is

c.positively charged