6 What would be the effect of a mutation in the coding regio

6. What would be the effect of a mutation in the coding region of the lactase gene?

Solution

first we neew to understand what is lactase

Lactase is a enzyme which can break down lactose sugar into galactose and glucose. this enzyme is essential for digestion of milk which contain high lactose sugar, you might heard word lactose intolerant, these means particular person lack of enzyme. Cannot digest milk,

If mutation in lactase gen codon there are two possibility

1. gain of mutation- in this case person gain the mutation and increase in high m-RNA expression of lactase gen so the enzyme activity high in particular person body to digest lactose so .this person come under lactase persistent phenotypes

2. loss of mutation- in this case person lactase intolerant due to mutation in lactase gen codon so there is low m-RNA expression and low lactase enzyme production, so this called lactase lactase nonpersistent phenotyp