We have learned that there is a huge influx and outflux of i

We have learned that there is a huge influx and outflux of ions during an action potential but what is this change as compared to the total number of ions present in cytoplasm. In this problem you are trying to find some numbers to answer this question. For the purpose of this problem only consider Na^* and K^+, Comment on your answers.

Solution

At resting membrane potential, the cell membrane is negatively charged at -70mV. Potassium ions (K+) are maintained at high concentrations within the cell, while sodium ions (Na+) are maintained at high concentrations outside of the cell.The neurons have more potassium leakage channels than sodium leakage channels. Therefore, potassium diffuses out of the cell at a much faster rate than sodium leaks in. More cations leaving the cell than entering it causes the interior of the cell to be negatively charged relative to the outside of the cell.