Please explain your steps and show your work Thank You 6 15

6. (15 points) Shown below are 4 mportant ons important to maintaining the tertiary fold of the protein. Identity each interaction and briefly describetheirimportancein maintainingatertiaryfold. 1. Type Explanation: 2.Type Explanation: ype Explanation: Type Explanation: Draw a new Diagram 2 that includes aSINGLE amino acid substitution that DOES NOTCHANGE the interactions indicated. Draw anew Diagram 3 thatincludes a SINGLE amino acid substitution that CHANGESThe interactions indicated.

Solution

Answer= The interactions for maintaining tertiary structure of protenis are

2] Hydrogen bond = folding is stabilized by hydrogen bonds

Hydrogen bonds can bring together two parts of a chain that are some distance away from in terms of sequence

Proteins 3 D structure is depend on hydrogen bonds

3] Ionic bond =Can be formed as amino acids bearing opposite electrical charges . these are important for protein structure they are potent electrostatic attraction that can approach the strength of covalent bonds

4] Hydrophobic interactions =Major force protein driving

Forms an interior hydrophobic protein core where most hydrophobic side chains can closely associate & are shielded from interactions with solvent H2O