Why does endocrine signaling result in a longterm response Q

Why does endocrine signaling result in a long-term response? Question 24 options: A. The hormone is bound covalently to the receptor B. The hormone is metabolized slowly C. The receptor has a high affinity for hormone D. There is a high concentration of hormone in blood E. There is a rapid rate of synthesis of hormone

Solution

The correct answer would be :  C. The receptor has a high affinity for hormone .

Reason:There occurs a tight binding between the receptor and the hormone that is highy stable and this results in long term response.