Suppose the reaction A B rightarrow C D has a Delta g of

Suppose the reaction A + B rightarrow C + D has a Delta g of + 5.2 kcal/mol. If this reaction is coupled to the reaction ATP+ H_2O rightarrow ADP + P_i, which has a Delta g of -7.3 kcal/mol. What will be the change in free energy of the combined reaction, and will the erection spontaneous? Explain your answer.

Solution

The change in the free energy of the combined reaction is -2.1 kcal/mol (5.2-7.3) which is a spontaneous reaction.

At equilibrium constant k(eq) greater than one (1) where products are more than reactants, the G is negative. which always indicate spontaneous reaction. if G is zero reaction is in equilibrium. if it is positive the reaction is in reverse direction