Insulins interaction with glucagon could be described as an

Insulin\'s interaction with glucagon could be described as a(n): permissive effect. synergistic effect. antagonistic effect. marginal effect.

Solution

Answer:

Insulin and Glucagon interaction could be described as ANTAGONISTIC EFFECT.

Because,

Glucagon ( also called Hyperglycemia- Glucosuria Factor or HG factor) raises Blood Sugar by-

1) Enhancing hepatic glycogenolysis

2) Increasing hepatic gluconeogenesis from amino acids

3) Decreasing hepatic glycogenesis and by

4) inhibiting glucose utilisation through c-AMP mediated phosphorylation and inactivation of pyruvate kinase and pyruvate dehydrogenase

On the other hand Insulin inhibits glucagon secration by paracrine action of the Alpha- cells and causes lowering of blood sugar by

1) increasing utilisation of glucose in energy production and lipogenesis

2) lowring glucose formation frpm glycogen

3) indirectly enhancing carbohydrate storage as glycogen in muscle and liver .

Thus Insulin and Glucagon interaction could be described as ANTAGONISTIC EFFECT.