The human clotting factor X and neuraminadase genes are link

The human clotting factor X and neuraminadase genes are linked on chromosome 12. Imagine that you measure the genetic map distance between these genes in females and determine this to be 16 cM with the genes separated by 16 mB (one mB is one million base pairs of DNA). If you repeated this study in males, what would you estimate the spacing of these genes to be in mB?

Solution

Both men and women are having 22 pairs of chromosomes (somatic chromosomes) in common.

Men are having 22 pairs of somatic chromosomes and a pair of sex chromosomes XY

women are having 22 pairs of somatic chromosomes and a pair of sex chromosomes XX

Since the human clotting factor X and neuraminadase genes are linked on 12 chromosome (somatic chromosome) there will be no difference in the distance between these two genes in men and women