Describe examples of variant histones and the chromosomal st
Describe examples of variant histones and the chromosomal structures and/or processes with which each is associated?
Solution
Answer : Histones are the basic proteins that contain high amounts of basic amino acids such as arginine and lysine. They play a role in packaging eukaryotic DNA into structural units called nucleosomes. There are five types of histone proteins in eukaryotic chromosomes namely, H1, H2A, H2B, H3 and H4. H1 is called the linker histone and highly conserved and the last four histones in copies of two forms the histone octamer found at the centre of nucleosome. Apart from its involvement in DNA packaging they also have a vital role in eukaryotic gene regulation which is brought about by acetylation and deacetylation of histone proteins
