Which of these statements about transcriptional regulators i

Which of these statements about transcriptional regulators is TRUE? If false, correct it so it reads true. Transcriptional regulators usually interact with the sugar-phosphate backbone on the outside of the double helix to determine where to bind on the DNA helix. Transcriptional regulators will form hydrogen bonds, ionic bonds, and hydrophobic interactions with DNA. The DNA-binding motifs of transcriptional regulators usually bind in the minor groove of the DNA helix. The binding of transcriptional regulators generally does not disrupt the hydrogen bonds that hold the double helix together.

Solution

a. The statement is false. The correct statement is: Transcriptional regulators bind to specific sequences like promoters on the DNA double helix which is a region containing all the three constituents of DNA - Sugar, phosphate and nitrogenous bases.

b. The statement is true.

c. The statement is false. The correct statement is: The DNA - binding motifs of transcriptional regulators usually bind in the major groove of the DNA helix.

d. The statement is true.